CHRISTOPHER J. KRATOCHVIL, MD
Associate Professor of Psychiatry
University of Nebraska Medical Center
985581 Nebraska Medical Center
Omaha, Nebraska 68198-5581
(402) 354-6868

Biography

Christopher J. Kratochvil, MD, is an Associate Professor in the Department of Psychiatry and a member of the Graduate Faculty at the University of Nebraska Medical Center (UNMC). He is also Assistant Director of the Psychopharmacology Research Consortium at UNMC.

Board certified in Psychiatry as well as Child and Adolescent Psychiatry, Dr. Kratochvil received both his Bachelor of Arts and medical degrees from Creighton University in Omaha, Nebraska. He completed a residency in Psychiatry at the Creighton-Nebraska Joint Residency Program and was named Associate Chief Resident from 1994 to 1995. He went to Duke University Medical Center, where he completed a residency in Child and Adolescent Psychiatry and served as Chief Resident from 1996 to 1997.

He is currently a member of the American Academy of Child & Adolescent Psychiatry, the American Psychiatric Association, the American Medical Association, the Applied Research Ethics Association, the Nebraska Regional Council of Child & Adolescent Psychiatry, and the Nebraska Psychiatric Association. He is president of the Nebraska Regional Council of Child & Adolescent Psychiatry.

Dr. Kratochvil's current interests are in areas related to attention deficit hyperactivity disorders (ADHD), pediatric depression, and genetics of psychiatric disorders. He is well published in both books and professional journals and has vast experience working on grants.

Recent Publications

Journal Articles

Kratochvil, C. J., Varley, C., Cummins, T. K., & Martin, A. (in press). Less is more: Inpatient management of a child with complex pharmacotherapy. Journal of the American Academy of Child and Adolescent Psychiatry.

Kratochvil, C. J., Vitiello, B., Walkup, J., Emslie, G., Waslick, B. D., Weller, E. B., Burke, W. J., & March, J. S. (2006). SSRIs in pediatric depression: Is the balance between benefits and risks favorable? Journal of Child and Adolescent Psychopharmacology, 16, 151-164.

Kratochvil, C. J., Vitiello, B., Brent, D., Bostic, J. Q., & Naylor, M. W. (2006). Selecting an antidepressant for the treatment of pediatric depression. Journal of the American Academy of Child and Adolescent Psychiatry, 45, 371-373.

Wilens, T. E., Kratochvil, C. J., Newcorn, J., Thomason, C., & Gao, H. (2006). Do children and adolescents with ADHD respond differently to atomoxetine? Journal of the American Academy of Child and Adolescent Psychiatry, 45, 149-157.

Madaan, V., Kinnan, S., Daughton, J., & Kratochvil, C. J. (2006). Innovations and recent trends in the treatment of ADHD: A review. Expert Review of Neurotherapeutics, 6, 1375-1385.

Deupree, J. D., Smith, S. D., Kratochvil, C. J., Bohac, D., Ellis, C. R., Polaha, J., & Bylund, D. B. (2006) Possible involvement of Alpha-2A Adrenergic Receptors in attention deficit hyperactivity disorder: Radioligand binding and polymorphism studies. Neuropsychiatric Genetics.

Sankaranarayanan, J. M., Pharm Puumala, S. E., & Kratochvil, C. J. (2006). Diagnosis and treatment of adult attention-deficit/hyperactivity disorder in U.S. ambulatory care from 1996 to 2003. Current Medical Research and Opinion, 22, 1475-1491.

Kratochvil, C. J., Wilens, T. E., & Upadhyaya, H. (2006). Pharmacological management of a youth with ADHD, marijuana use, and mood symptoms. Journal of the American Academy of Child Adolescent Psychiatry, 45, 1138-1141.

Wilens, T., McBurnett, K., Buckstein, O., McGough, J., Greenhill, L., Lerner, M., Stein, M. A., Conners, C. K., Duby, J., Newcorn, J., Bailey, C. E., Kratochvil, C. J., Coury, D., Casat, C., Denisco, M. J., Halstead, P., Bloom, L., Zimmerman, B. A., Gu, J., Cooper, K., & Lynch, J. M. (2006). A multisite, controlled trial of OROS® methylphenidate (CONCERTA®) in the treatment of adolescents with attention-deficit/hyperactivity disorder. Archives of Pediatrics & Adolescent Medicine, 160, 82-90.

Kratochvil, C. J., Egger, H., Greenhill, L. L., & McGough, J. (2006). Pharmacological management of preschool ADHD. Journal of the American Academy of Child and Adolescent Psychiatry, 45,115-118.

Kratochvil, C. J., Kazura, A., Deas, D., Martin, C. A., Dosh, T., & Wilens, T. E. (2006). Pharmacological management of a teen with significant alcohol use and depression. Journal of the American Academy of Child Adolescent Psychiatry, 45, 1011-1015.

Wilens, T., Newcorn, J., Kratochvil, C. J., Gao, H., Thomason, C. K., Rogers, A. K., Feldman, P., & Levine, L. (2006). Long-term atomoxetine treatment in adolescents with attention-deficit/hyperactivity disorder. Journal of Pediatrics, 149, 118-125.

Kratochvil, C. J., Wilens, T. E., Greenhill, L. L., Gao, H., Baker, K. D., Feldman, P. D., & Gelowitz, D. L. (2006). Effects of long-term atomoxetine treatment for young children with attention-deficit/hyperactivity disorder. Journal of the American Academy of Child Adolescent Psychiatry, 48, 919-927.

Brown, R. T., Perwien, A., Faries, D. E., Kratochvil, C. J., & Vaughan, B. S. (2006). Atomoxetine in the management of children with ADHD: Effects on quality of life and school functioning. Clinical Pediatrician, 45, 819-827.

Kratochvil, C. J., March, J., & Prentice, E. (2006). Guidance for IRB's on placebo and alternatives to placebo in randomized controlled trials. The Bureau of National Affairs, 5, 220-224.

Pathak, S., Kratochvil, C. J., Rogers, G. M., Silva, S., Vitiello, B., Weller, E. B., & March, J. S. (2005). Comparative efficacy of cognitive behavioral therapy, fluoxetine, and their combination in depressed adolescents: Initial lessons from the treatment for adolescents with depression study. Current Psychiatry Reports, 7, 429-434.

Biederman, J., Swanson, J. M., Wigal, S. B., Kratochvil, C. J., Boellner, S. W., Earl, C. Q., Jiang, J., & Greenhill, L. L. (2005). Efficacy and safety of modafinil film-coated tablets in children and adolescents with attention-deficit/hyperactivity disorder: Results of a randomized, double-blind, placebo-controlled, flexible-dose study. Pediatrics, 116, 777-84.

Kratochvil, C. J., DelBello, M., Upadhyaya, H., & Wozniak, J. (2005). Pharmacological management of new-onset bipolar disorder. Journal of the American Academy of Child and Adolescent Psychiatry, 44, 1198-1200.

Kratochvil, C. J., Newcorn, J. H., Arnold, L. E., Duesenberg, D., Emslie, G. J., Quintana, H., Sarkis, E. H., Wagner, K. D., Gao, H., Michelson, D., & Biederman, J. (2005). Atomoxetine alone or combined with fluoxetine for treating ADHD and comorbid depressive or anxiety symptoms. Journal of the American Academy of Child and Adolescent Psychiatry, 44, 915-924.

Kratochvil, C. J., Findling, R. L., McDougle, C. J., Scahill, L., & Hamarman, S. (2005). Pharmacological management of agitation and aggression in an adolescent with autism. Journal of the American Academy of Child and Adolescent Psychiatry, 44, 829-832.

Kratochvil, C. J., Simons, A., Vitiello, B., Walkup, J., Emslie, G., Rosenberg, D., & March, J. S. (2005). A multi-site psychotherapy and medication trial for depressed adolescents: Background and benefits. Cognitive and Behavioral Practice, 12, 159-165.

Ginsburg, G. S., Albana, A. M., Findling, R. L., Walkup, J., & Kratochvil, C. J. (2005). Integrating cognitive behavioral therapy and pharmacotherapy in the treatment of adolescent depression. Cognitive and Behavioral Practice, 12. Available from http://www.aabt.org/publication/cbp/c%26bp12.2.html

Weiss, M., Tannock, R., Kratochvil, C. J., Dunn, D., Velez-Borras, J., Thomason, C., Tamura, R., Kelsey, D., Stevens, L., & Allen, A. J. (2005). A randomized, placebo-controlled study of once-daily atomoxetine in the school setting in children with ADHD. Journal of the American Academy of Child and Adolescent Psychiatry, 44, 647-655.

Kratochvil, C. J., Lake, M., Pliszka, S. R., & Walkup, J. T. (2005). Psychopharmacology perspectives: Pharmacological management of treatment-induced insomnia in ADHD. Journal of the American Academy of Child and Adolescent Psychiatry, 44, 499-501.

Spencer, T., Newcorn, J., Kratochvil, C. J., Ruff, D., Michelson, D., & Biederman, J. (2005). Effects of atomoxetine on growth after 2-year treatment in pediatric patients with ADHD. Pediatrics, 116, e74-e80.

Polaha, J., Cooper, S., Meadows, T., & Kratochvil, C. J. (2005). The assessment of attention-deficit/hyperactivity disorder in rural primary care: The portability of the American Academy of Pediatrics guidelines to the 'real world'. Pediatrics, 115, 120-126.

Kratochvil, C. J., Dineen Wagner, K., Emslie, G., & March, J. (2005). Pharmacological management of treatment-resistent pediatric depression. Journal of the American Academy of Child and Adolescent Psychiatry, 44, 198-200.

Treatment for Adolescents with Depression Study (TADS) Team. (2005). The treatment for adolescents with depression study (TADS): Demographic and clinical characteristics. Journal of the American Academy of Child and Adolescent Psychiatry, 44, 28-40.

Kratochvil, C. J., Greenhill, L. L., March, J. S., Burke, W. J., & Vaughan, B. S. (2004). The role of stimulants in the treatment of preschool children with attention-deficit hyperactivity disorder. CNS Drugs, 18, 957-966.

Treatment for Adolescents with Depression Study (TADS) Team. (2004). Fluoxetine, cognitive-behavioral therapy, and their combination for adolescents with depression: Treatment for adolescents with depression study (TADS) randomized controlled trial. Journal of the American Medical Association, 292, 807-820.

Kratochvil, C. J., Vaughan, B. S., Daughton, J. M., Mayfield-Jorgensen, M. L., & Burke, W. J. (2004). Atomoxetine in the treatment of attention deficit hyperactivity disorder. Expert Review Neurotherapeutics, 4, 601-611.

March, J., Kratochvil, C., Clarke, G., Beardslee, W., Derivan, A., Emslie, G., Green, E. P., Heiligenstein, J., Hinshaw, S., Hoagwood, K., Jensen, P., Lavori, P., Leonard, H., McNulty, J., Michaels, A., Mossholder, A., Osher, T., Petti, T., Prentice, E., Vitiello, B., & Wells, K. (2004). AACAP 2002 research forum: Placebo and alternatives to placebo in randomized controlled trials in pediatric pharmacology. Journal of the American Academy of Child and Adolescent Psychiatry, 43, 1046-1056.

Hinshaw, S. P., Hoagwood, K., Jensen, P. S., Kratochvil, C. J., Bickman, L., Clarke, G., Abikoff, H. B., Atkins, M., & Vitiello, B. (2004). AACAP 2001 research forum: Challenges and recommendations regarding recruitment and retention of participants in research investigations. Journal of the American Academy of Child and Adolescent Psychiatry, 43, 1037-1045.

Matza, L. S., Rentz, A. M., Swensen, A. R., Secnik, K., Revicki, D. A., Michelson, D., Spencer, T., Newcorn, J., & Kratochvil, C. J. (2004). The link between health-related quality of life and clinical symptoms in children with ADHD. Journal of Developmental and Behavioral Disorders, 25, 166-174.

Perwien, A. R., Faries, D. E., Kratochvil, C. J., Sumner, C. R., Kelsey, D. K., & Allen, A. J. (2004). Improvement in health-related quality of life in children with ADHD: An analysis of placebo-controlled studies of atomoxetine. Journal of Developmental and Behavioral Pediatrics, 25, 264-271.

Lowe, N., Kirley, A., Hawi, Z., Sham, P., Wickham, H., Kratochvil, C. J., Smith, S. D., Lee, S. Y., Levy, F., Kent, L., Middle, F., Rohde, L. A., Roman, T., Tahir, E., Yazgan, Y., Asherson, P., Mil,l J., Thapar, A., Payton, A., Todd, R. D., Stephens, T., Ebstein, R. P., Manor, I., Barr, C. L., Wigg, K. G., Sinke, R. J., Buitelaar, J. K., Smalley, S. L., Nelson, S. F., Biederman, J., Faraone, S. V., & Gill, M. (2004). Joint analysis of DRD5 marker concludes association with ADHD confined to the predominantly inattentive and combined subtypes. American Journal of Human Genetics, 74, 348-356.

Kratochvil, C. J., Vaughan, B. S., Harrington, M. J., & Burke, W. J. (2003). Atomoxetine: A selective norepinephrine reuptake inhibitor for the treatment of attention-deficit/hyperactivity disorder. Expert Opinion on Pharmacology, 4, 1165-1174.

Kratochvil, C. J., Harrington, M. J., Burke, W. J., & Vaughan, B. S. (2003). Atomoxetine: Treatment of attention-deficit/hyperactivity disorder through selective norepinephrine reuptake inhibition. Today's Therapeutic Trends, 21, 239-250.

Biederman, J., Kratochvil, C. J., Spencer, T. J., & Wozniak, J. (2003). Determining and achieving therapeutic targets in attention-deficit/hyperactivity disorder. Journal of Clinical Psychiatry, 64, 265-276.

The Treatment of Adolescent Depression Study (TADS) Team. (2003). Treatment for adolescents with depression study (TADS): Rationale, design and methods. Journal of the American Academy of Child & Adolescent Psychiatry, 42, 531-542.

Greenhill, L. L., Jensen, P. S., Abikoff, H., Blumer, J. L., DeVeaugh-Geiss, J., Fisher, C., Hoagwood, K., Kratochvil, C. J., Lahey, B. B., Laughren, T., Leckman, J., Petti, T. A., Pope, K., Shaffer, D., Vitiello, B., & Zeanah, C. (2003). Developing strategies for psychopharmacological studies in preschool children. Journal of the American Academy of Child & Adolescent Psychiatry, 42, 406-414.

Biederman, J., Heiligenstein, J., Faries, D., Galil, N., Dittman, R., Emslie, G. J., Kratochvil, C. J., Laws, H., Schuh, K. J., & the Atomoxetine Study Group. (2002). Efficacy of atomoxetine versus placebo in school-age girls with attention-deficit/hyperactivity disorder. Pediatrics, 110. Available from http://www.pediatrics.org/cgi/content/full/110/6/e75

Spencer, J. T., Heiligenstein, J. H., Biederman, J., Faries, D. E., Kratochvil, C. J., Conners, C. K., & Potter, W. Z. (2002). Results from 2 proof-of-concept, placebo-controlled studies of atomoxetine in children with attention-deficit/hyperactivity disorder. Journal of Clinical Psychiatry, 63, 1140-1147.

Wernicke, J. F., & Kratochvil, C. J. (2002). Safety profile of atomoxetine in the treatment of children and adolescents with ADHD. Journal of Clinical Psychiatry, 63, 50-55.

Kratochvil, C. J., Harrington, M. J., Burke, W. J., & March, J. S. (2002). Pharmacotherapy of childhood anxiety disorders. Current Psychiatric Reports, 4, 264-269.

Michelson, D., Allen, A. J., Kelsey, D., Busner, J., Casat, C., Dunn, D., Kratochvil, C. J., Newcorn, J., Sallee, F. R., Sangal, R. B., Saylor, K., West, D., Wernicke, J., Raute, N., & Harder, D. (2002). Safety and efficacy of once-daily atomoxetine versus placebo in children and adolescents with attention-deficit/hyperactivity disorder. American Journal of Psychiatry, 159, 1896-1901.

Burke, W. J., & Kratochvil, C. J. (2002). Stereoisomers in psychiatry. The case of escitalopram. Primary Care Companion to the Journal of Clinical Psychiatry, 4, 20-24.

Kratochvil, C. J., Heiligenstein, J., Spence, T., Biederman, J., Wernicke, J., Newcorn, J., Casat, C., & Michelson, D. (2002). Atomoxetine and methylphenidate treatment in children with ADHD: A prospective, randomized, open-label trial. Journal of the American Academy of Child & Adolescent Psychiatry, 41, 776-784.

Book Chapters

Kratochvil, C. J., Prentice, E. D., Gordon, B. G., & Kotulak, G. D. (2006). Regulatory issues of research involving prisoners. In E. A. Bankert & R. J. Amdur (Eds.), Institutional Review Board: Management and Function, Second Edition. Boston: Jones & Bartlett.

Kratochvil, C. J., Prentice, E. D., Epperson, K. J., & Gordon, B. G. (2006). Institutional Review Board Review of adverse events. In E. A. Bankert & R. J. Amdur (Eds.), Institutional Review Board: Management and function, Second Edition. Boston: Jones & Bartlett.

Gordon, B. G., Brown, J. S., Kratochvil, C. J., & Schonfeld, T. L. (2006). Paying research subjects. In E. A. Bankert & R. J. Amdur (Eds.), Institutional Review Board: Management and function, Second Edition. Boston: Jones & Bartlett.

Kratochvil, C. (2006). Contributing author (questions and text). Study guide for Institutional Review Board management and function. Edited by A. L. Davis, E. A. Bankert, K. Hansen, S. Kornetsky, & H. McGough. Jones & Bartlett Publishers.

Kratochvil, C., & Harrington, M. (2003). Adolescent interpersonal relationships. In R. Rosen (Ed.). Textbook of adolescent psychiatry (193-198). London: Arnold.

Kratochvil, C., & Contributing Author (questions and text). (2002). Study guide for Institutional Review Board: Management and function. In S. Kornetsky, A. Davis, & R. J. Amdur (Eds.), Institutional Review Board: Management and function. Boston: Jones & Bartlett.

Gordon, B., Brown, J., Kratochvil, C. J., & Prentice, E. (2002). Paying research subjects. In R. Amdur (Ed.). Institutional Review Board: Member Handbook (105-112). Boston: Jones & Bartlett.

Prentice, E. D., Gordon, B. G., Kratochvil, C. J., & Kotulak, G. D. (2002). Research involving prisoners. In R. Amdur & E. Banker (Eds.), Institutional Review Board: Member Handbook (171-174). Boston: Jones & Bartlett.

Prentice, E. D., Epperson, K. J., Kratochvil, C. J., & Gordon, B. (2002). IRB review of adverse events. In R. Amdur & E. Banker (Eds.), Institutional Review Board: Management and function (297-302). Boston: Jones & Bartlett.

Gordon, B., Brown, J., Kratochvil, C. J., & Prentice, E. (2002). Paying research subjects. In R. Amdur & E. Banker (Eds.), Institutional Review Board: Management and function (185-190). Boston: Jones & Bartlett.

Prentice, E. D., Gordon, B. G., Kratochvil, C. J., & Kotulak, G. D. (2002). Research involving prisoners. In R. Amdur & E. Banker (Eds.), Institutional Review Board: Management and function (394-398). Boston: Jones & Bartlett.

 

Research Projects

A Multi-Center Study of the Validity, Reliability, and Consumer Satisfaction of the Pediatric Adverse Event Rating Scale (PAERS); A Likert-Style Adverse Event Reporting Questionnaire
National Institute of Mental Health
Role: PI	2005-Present

Substance Use Outcomes Following Treatment for Adolescent Depression (SOFTAD)
National Institute of Mental Health
Role: PI	2004-Present

Pharmacological Treatment of ADHD in Young Children
National Institute of Mental Health
Role: PI	2003-Present

Genetic Linkage Study of Children with Attention Deficit Hyperactivity Disorder
National Institute of Mental Health
Role: PI	2003-Present

Treatment for Adolescents with Depression Study (TADS)
National Institute of Mental Health
Role: PI	1999-Present